ENGINEERING
PHA.SE. supports its Clients on dedicated Engineering services, from the provision of layout analysis (considering also material and personnel flows) to the design support on developing and/or revamping of manufacturing and ancillary areas (either individual departments and entire manufacturing sites). PHA.SE. realizes inspection and review to the facility, organization and documentation of its own client accordingly to international standards and current regulation.
PHA.SE. realizes for its own Client a detailed Report pointing out the investigation areas. If required PHA.SE. realizes an investment evaluation applicable for a possible solution. PHA.SE. realizes Engineering services considering also its own GxP background which guarantee the development of every project phase taking cGMP problems into account. PHA.SE. may be a reliable partner for the following activities.
Conceptual Design
- Client URS definition
- Lay-out and Process Flow Diagrams definition
- Production plant and technical plant Areas definition
- Personnel/Material flow definition
- P&IDs definition for Process and technical utilities
- GMP reviews
- Total Investment Cost Estimate (± 25 ÷ 30%)
Detailed Design
- Technical Follow up of the orders
- Inspection and Expediting
- GxP Reviews
- Design Qualification protocols/procedures
preparation & execution
Construction Phase
- Construction management
- Utilities, Facilities and Equipment Installation
- Mechanical completion follow up
- Punch List management
Basic Design
- Consolidate what defined during Conceptual Design
- Process Equipment Lay-out
- Process Utilities Generation and Distribution Lay-Out
- Design Criteria HVAC
- P&ID HVAC
- Process and technical fluids P&ID
- Process P&ID
- Piping Lay-Out
- Duct Lay-out
- Main utilities generation equipment Pre-dimensioning
- Equipment list
- Instruments list
- Fluids list
- Consumption list
- Activities time table
- Technical specification for inquiry
- Vendor Auditing
- Technical and economical tabulation
and alignment of the offers - Technical specification for order
- Total Investment Cost Estimate (± 10 ÷ 15%)
